�ESBATech AG, a preeminent developer of antibody fragment therapeutics,
announced that the company has successfully accomplished its Phase I clinical
study of the company's lead product candidate, ESBA105, in ophthalmic
indications. In April 2008, ESBATech initiated the Phase I study designed to
evaluate the safety, tolerability and pharmacokinetic profile of ESBA105,
when delivered locally via eye drops in healthy volunteers. This run was
conducted as a single and repeated dose escalation sketch in Switzerland.
ESBA105 is a single-chain antibody fragment directed against TNF-alpha, and
it is being developed initially for ophthalmic indications. Several
additional clinical studies are in the
Monday, 8 September 2008
Tuesday, 19 August 2008
Metallica Announce U.S. Tour Dates
Metallica stimulate announced their 'Death Magnetic' U.S. turn, which will run from October 21st of this year, right through until January 31st 2009.
The metal rockers will play 32 shows across four months, joined by support bands Down and The Sword, Lamb of God and Machine Head.
Metallica will predate the dates by cathartic 'Death Magnetic' on September 12th.
October Tour Dates:
Glendale, AZ, Jobing Arena � 21
Albquerque, NM, Tingley Coliseum - 23
Kansas City, MO, Sprint Center - 25
Des Moines, IA, Wells Fargo Arena - 26
November Tour Dates:
Portland, OR, Rose Quarter � 1
Salt Lake City, UT, Energy Solutions Arena - 3
Denver, CO, Pepsi Center - 4
Omaha, NE, Qwest Center - 6
Moline, IL, iWireless Center - 8
Columbus, OH, Schottenstein Center - 9
St. Louis, MO, Scottrade Center - 17
Tulsa, OK BOK, Center - 18
Houston, TX ,Toyota Center - 20
Little Rock, AR, Alltel Arena - 22
New Orleans, LA, New Orleans Arena � 23
December Tour Dates:
Seattle, WA, Key Arena � 1
Vancouver, BC, GM Place - 2
Calgary, AB, Pengrowth Saddledome - 4
Edmonton, AB, Rexall Place - 7
Ontario, CA, Citizens Bank Arena - 8
Fresno, CA, Save Mart Center - 13
San Diego, CA ,Cox Arena - 15
Los Angeles, CA, The Forum - 17
Oakland, CA, Oracle Arena � 20
January 2009 Tour Dates:
Milwaukee, WI, Bradley Center - 12
Detroit, MI Joe Louis Arena - 13
Washington, DC, Verizon Center - 15
Philadelphia, PA ,Wachovia Center - 17
Boston, MA TD, Banknorth Center - 18
Chicago, IL, Allstate Arena - 26
Uniondale, NY, Nassau Coliseum - 29
Newark, NJ, Prudential Center - 31
More info
Saturday, 9 August 2008
Legion Of Doom
Artist: Legion Of Doom
Genre(s):
Metal: Death,Black
Discography:
A Decade Of Darkness and Blood
Year: 2000
Tracks: 14
Kingdom Of Endless Darkness
Year: 1995
Tracks: 7
Tuesday, 1 July 2008
Wisdom In Chains
Artist: Wisdom In Chains
Genre(s):
Rock
Hardcore
Discography:
Die Young
Year: 2007
Tracks: 17
Class War
Year: 2007
Tracks: 17
Self Titled
Year: 2002
Tracks: 11
Rocked the Nation - the final 10
Monday, 23 June 2008
Bob Brown
Artist: Bob Brown
Genre(s):
Techno
Discography:
Series Primary Yellow (FW02)
Year: 1999
Tracks: 4
Series Primary Blue
Year: 1999
Tracks: 4
Rundfunkchor Leipzip, Staatskapelle Dresden
Wednesday, 18 June 2008
Curlew
Artist: Curlew
Genre(s):
Rock
Trance
Discography:
North America
Year: 2002
Tracks: 13
Titolo sconosciuto
Year:
Tracks: 10
Curlew was formed in 1979 by George Cartwright, world Health Organization serves as the group's loss leader, saxophonist and main composer. The other members of Curlew are presently electric guitarists Davey Williams and Chris Cochrane, bassist Ann Rupel and drummer Kenny Wollesen. Although Cartwright is a native Southerner, and brings something of a roadhouse, R&B tittup to his music, Curlew was founded in New York, and has been part of the hip, NYC "business district" scene since its origin. Over the old age, with Cartwright and Williams as the group constants, Curlew has been something of an incubator and showcase for NYC avant malarky talent. Maverick keyboardist Wayne Horvitz played on Curlew's third album, Live in Berlin. Cellist Tom Cora was an early member, and is featured on several Curlew releases; Cora was besides a founding extremity of Skeleton Crew with Fred Frith and has played with such artists as Eugene Chadbourne and John Zorn. Original Curlew drummer Pippin Barnett was a instauration member of the Orthotonics and performed with Cora in the Swiss group Nimal. He was replaced in Curlew by Samm Bennett, world Health Organization was besides a extremity of Third Person, a triad which included Cora. Bennett is besides drummer for the NYC jazz/rock band Chunk. Current bassist Ann Rupel plays in the group No Safety, along with Curlew guitarist Cochrane. And one of Curlew's more data-based releases, the 1993 Beautiful Western Saddle, featured isaac M. Singer Amy Denio and lyrics by poet Paul Haines. This diverse energy has unbroken Curlew on the creative cutting boundary throughout its history, and whatsoever particular version of the band is filled with surprises and dynamic musical interactions. Among Curlew's standout recordings are the no-holds-barred 1986 recording Live in Berlin, 1996's Paradise, and their 1998 release, Mythologic Drop.
Tuesday, 17 June 2008
Brad, Ange splash out on nursery
Brad Pitt and Angelina Jolie have splashed out $US140,000 on a nursery for their twins.
The couple, who are set to welcome two new daughters this month, reportedly hired exclusive Los Angeles baby boutique Petit Tresor to design a luxurious suite for the latest additions to their family.
Items purchased by Brad and Angelina are believed to include two pink crystal chandeliers worth $899 each, $3200 'Versailles-style' cribs and matching $2800 changing tables, organza bassinets worth $800 and $4500 French wardrobes.
he couple also splashed out on cashmere baby toys for their unborn babies.
A team of three Petit Tresor staff were hired to assemble the nursery, according to the New York Daily News newspaper.
Brad and Angelina - who already have three adopted children, six-year-old Maddox, four-year-old Pax and Zahara, three, along with a two-year-old biological daughter Shiloh - are not the only celebrity couple to spend a fortune on a nursery.
Jennifer Lopez and Marc Anthony are said to have ordered a $50,000 nursery from Petit Tresor in preparation for the arrival of their twins in February.
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